CN009543V

CN009543V is an epidermal growth factor receptor (EGFR) agonist. CN009543V enhances tyrosine phosphorylation of EGFR at Tyr1068 and Tyr1173, thereby activating the MAPK/ERK cascade. CN009543V inhibits the activity of PTP-1B in MDA MB468 cells. CN009543V can be used in cancer research .


Cat. No.: EX-A9538	Purity: >98%

	Chemical structure of CN009543V

For research only, Do not use for Human!

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CAS No.	375826-84-9
Purity	>98%
Formula	C12H12N4O6S
Mol Weight	340.312
Color	Light yellow to yellow
State	Solid
Solubility	soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder -20℃ 3 years, 4℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Sakanyan V, et al. Screening and discovery of nitro-benzoxadiazole compounds activating epidermal growth factor receptor (EGFR) in cancer cells. Sci Rep. 2014;4:3977. Published 2014 Feb 5.
CoA	CoA of CN009543V

Smiles:	O=C(OC)C(NC(=O)C)CSC1=CC=C(C2=NON=C21)N(=O)=O


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