CMP-5

CMP-5 is a potent, specific, and selective PRMT5 inhibitor. CMP-5 selectively blocks S2Me-H4R3 by inhibiting PRMT5 methyltransferase activity on histone preparations. CMP-5 prevents Epstein-Barr virus (EBV)-driven B-lymphocyte transformation but leaving normal B cells unaffected.


Cat. No.: EX-A7640	Purity: >98%

	Chemical structure of CMP-5

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	685	In-stock
200mg	985	In-stock
500mg	get quote	In-stock
1g	get quote	In-stock

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Synonyms	PRMT5-IN-5
CAS No.	880813-42-3
Purity	>98%
Formula	C21H21N3
Mol Weight	315.4115
Color	Light yellow to yellow
State	oil
Solubility	DMSO : 100 mg/mL
Shelf Life	>2 years if stored properly
Storage	Pure form -20℃ 3 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Alinari L, et al. Selective inhibition of protein arginine methyltransferase 5 blocks initiation and maintenance of B-cell transformation.Blood. 2015 Apr 16;125(16):2530-43. [2]. Webb LM, et al. PRMT5-Selective Inhibitors Suppress Inflammatory T Cell Responses and Experimental Autoimmune Encephalomyelitis. J Immunol. 2017 Feb 15;198(4):1439-1451.
CoA	CoA of CMP-5


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