Clathrin-IN-4

Clathrin-IN-4 (compound 8b), a Wiskostatin analogue, is a potent inhibitor of clathrin mediated endocytosis with an IC50 of 2.1 μM. Clathrin-IN-4 is a dynamin I GTPase activity inhibitor with an IC50 of 9.1 μM.


Cat. No.: EX-A7343	Purity: >98%

	Chemical structure of Clathrin-IN-4

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
25mg	450	In-stock
50mg	685	In-stock
100mg	985	In-stock
250mg	1485	In-stock
500mg	get quote	Inquire

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CAS No.	762242-59-1
Purity	>98%
Formula	C17H18Br2N2O
Mol Weight	426.146
Color	White to off-white
State	solid powder
Solubility	DMSO : 90 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Peter J Cossar, et al. Wiskostatin and other carbazole scaffolds as off target inhibitors of dynamin I GTPase activity and endocytosis. Eur J Med Chem. 2022 Dec 15;247:115001.
CoA	CoA of Clathrin-IN-4

Smiles:	CN(C[C@H](CN1C2=CC=C(C=C2C3=CC(Br)=CC=C31)Br)O)C


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