CL5D

CL5D is an activator of protein deacetylase SIRT6. CL5D can significantly enhance the deacetylation activity of SIRT6 and improve its catalytic efficiency. CL5D regulates SIRT6 activity by promoting conformational changes, especially dependent on the role of Arg-65 residue. CL5D can be used to study the activation mechanism of SIRT6 and its function in metabolism, DNA repair and aging.


Cat. No.: EX-A5821	Purity: >98%

	Chemical structure of CL5D

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	985	In-stock
100mg	1385	In-stock
250mg	2250	In-stock

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CAS No.	2488745-53-3
Purity	>98%
Formula	C29H11Cl7N2O6
Mol Weight	731.578
State	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Klein MA, et al. Mechanism of activation for the sirtuin 6 protein deacylase. J Biol Chem. 2020 Jan 31;295(5):1385-1399.
CoA	CoA of CL5D


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