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Product Information:

CK1α degrader-1

CK1α degrader-1 (Compound 82) is an orally active CK1α degrader with a DC50 of 0.105 μM. CK1α degrader-1 can be used for the research of cancer .

Cat. No.: EX-A9104    Purity: >98%
Chemical
Chemical structure of CK1α degrader-1


For research only, Do not use for Human!

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SynonymsCK1alpha degrader-1
CAS No.2881012-96-8
Purity>98%
FormulaC24H23ClN4O4
Mol Weight466.917
ColorWhite to off-white
StateSolid
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder -20℃ 3 years, 4℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Fu L, et al. Isoindolinone compounds, and uses thereof. WO2022257897A1. 2022-12-15.

CoACoA of CK1α degrader-1
Smiles:O=C1C2=CC=C(C(N[C@H](C3=CC=C(C=N3)Cl)C4CCC4)=O)C=C2CN1[C@@H]5C(NC(CC5)=O)=O

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