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Product Information:

CJ-13,610 hydrochloride

CJ-13,610 (hydrochloride) is an orally active and potent nonredox-type 5-lipoxygenase inhibitor with an IC50 value of 0.07 μM. CJ-13,610 (hydrochloride) competes with activating LOOH at a regulatory LOOH-binding site with high affinity, thereby preventing 5-lipoxygenase catalysis. CJ-13,610 (hydrochloride) is promising for research of diseases related to elevated levels of 5-lipoxygenase such as inflammatory reactions, allergic asthma, various types of cancer and atherosclerosis .

Cat. No.: EX-A10905    Purity: >98%
Chemical
Chemical structure of CJ-13,610 hydrochloride


For research only, Do not use for Human!

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CAS No.179420-27-0
Purity>98%
FormulaC22H24ClN3O2S
Mol Weight429.963
StateSolid
Shelf Life>3 years if stored properly
StoragePowder -20℃ 3 years; 4℃, 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Fischer L, et al. Molecular pharmacological profile of the nonredox-type 5-lipoxygenase inhibitor CJ-13,610. Br J Pharmacol. 2004;142(5):861-868.

CoACoA of CJ-13,610 hydrochloride
Smiles:NC(C1(C2=CC(SC3=CC=C(N4C(C)=NC=C4)C=C3)=CC=C2)CCOCC1)=O.Cl

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