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Product Information:

Cipepofol

Cipepofol (Ciprofol), a novel 2,6-disubstituted phenol derivative, is a positive allosteric modulator and direct agonist of the GABAA receptor. Cipepofol can cause the central nerve inhibition and promote sleep based on the structural modification of Propofol. Cipepofol can activate the sirtuin1 (Sirt1)/Nrf2 pathway. Cipepofol protects the heart against Isoproterenol-induced myocardial infarction by reducing cardiac oxidative stress, inflammatory response and cardiomyocyte apoptosis

Cat. No.: EX-A14136    Purity: >98%
Chemical
Chemical structure of Cipepofol


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg495In-stock
100mg792In-stock
250mg1190In-stock
500mg1610In-stock
1g2180In-stock


CAS No.1637741-58-2
Purity>98%
FormulaC14H20O
Mol Weight204.308
ColorColorless to light yellow
StateLiquid?Density?1.035
SolubilityDMSO : 100 mg/mL
Shelf Life>3 years if stored properly
StoragePure form -20°C, 3 years , 4°C, 2 years; In solvent -20°C, 1 month.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Ming Lu, et al. Ciprofol: A Novel Alternative to Propofol in Clinical Intravenous Anesthesia? Biomed Res Int. 2023 Jan 19:2023:7443226.

[2]. Yunzhao Yang, et al. Ciprofol attenuates the isoproterenol-induced oxidative damage, inflammatory response and cardiomyocyte apoptosis. Front Pharmacol. 2022 Nov 22:13:1037151.

CoACoA of Cipepofol
Smiles:C[C@H](C1CC1)C2=CC=CC(=C2O)C(C)C

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