CIM0216

CIM0216, a synthetic TRPM3 ligand, acts as a potent and selective agonist of TRPM3. CIM0216 exhibits selectivity for TRPM3 over TRPM1, TRPM2 and TRPM4-8. CIM0216 acts in a TRPM3-dependent manner to induce pain and evoke neuropeptide release from sensory nerve terminals in vitro. CIM0216 is a powerful tool for studies of the physiological functions of TRPM3, and can be used for neurogenic inflammation research .


Cat. No.: EX-A15498	Purity: >98%

	Chemical structure of CIM0216

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
500mg	456	in-stock
1g	635	in-stock
2g	1198	in-stock

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CAS No.	1031496-06-6
Purity	>98%
Formula	C21H21N3O2
Mol Weight	347.4103
Color	White to yellow
State	Solid
Solubility	soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder -20℃, 3 years; 4℃, 2 years; In solvent -20℃, 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Katharina Held, et al. Activation of TRPM3 by a potent synthetic ligand reveals a role in peptide release. Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):E1363-72.
CoA	CoA of CIM0216

Smiles:	CC1=CC(NC(C(C2=CC=CC=C2)N3C4=CC=CC=C4CCC3)=O)=NO1


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