Chk1-IN-5

Chk1-IN-5 is a potent checkpoint kinase 1 (Chk1) inhibitor. Chk1-IN-5 inhibits Chk1 phosphorylation and inhibits tumor growth in colon cancer xenograft mode.


Cat. No.: EX-A12482	Purity: >98%

	Chemical structure of Chk1-IN-5

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	400	In-stock
100mg	640	In-stock
250mg	1250	In-stock
500mg	2000	In-stock
1g	3200	In-stock
2g	5200	In-stock

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Synonyms	BEBT-260
CAS No.	2120398-39-0
Purity	>98%
Formula	C18H18FN7O2
Mol Weight	383.3796
Color	Light yellow to yellow
State	solid powder
Solubility	DMSO : 50 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder 4℃, sealed storage, away from moisture, 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Xiong Cai, et al. 3,5-disubstituted pyrazoles useful as checkpoint kinase 1 (chk1) inhibitors, and their preparations and applications. WO2017132928A1. [2]. Jiang K, et al. Medicine in Drug Discovery, 2024: 100185.
CoA	CoA of Chk1-IN-5

Smiles:	N#CC1=NC=C(N=C1)NC2=NNC(=C2)C=3C(OC)=CC(F)=CC3OCCCN


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