Chimmitecan

Chimmitecan is a potent topisomerase I inhibitor. Chimmitecan is also an active metabolite of simmitecan. Chimmitecan exhibits potent antitumor activities both in vitro and in vivo by inhibiting topoisomerase I.


Cat. No.: EX-A4320	Purity: >98%

	Chemical structure of Chimmitecan

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
250mg	485	In-stock
500mg	885	In-stock
1g	1585	In-stock
5g	5650	In-stock
10g	8650	In-stock
25g	get quote	In-stock

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CAS No.	185425-25-6
Purity	>98%
Formula	C23H20N2O5
Mol Weight	404.4153
State	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Hu Z, Sun Y, Du F, Niu W, Xu F, Huang Y, Li C. Accurate determination of the anticancer prodrug simmitecan and its active metabolite chimmitecan in various plasma samples based on immediate deactivation of blood carboxylesterases. J Chromatogr A. 2011 Sep 23;1218(38):6646-53. doi: 10.1016/j.chroma.2011.07.042. Epub 2011 Jul 23. PubMed PMID: 21839460.
CoA	CoA of Chimmitecan

Smiles:	CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=CC5=C(C=CC(=C5CC=C)O)N=C4C3=C2)O


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