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Product Information:

ChemR23-IN-3

ChemR23-IN-3 is a potent thiazole-based ChemR23 inhibitor with an IC80 value of 12 nM.

Cat. No.: EX-A12108    Purity: >98%
Chemical
Chemical structure of ChemR23-IN-3


For research only, Do not use for Human!

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CAS No.3032433-98-7
Purity>98%
FormulaC31H33N5O5S2
Mol Weight619.754
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Imaizumi T, et al. Discovery and mechanistic study of thiazole-4-acylsulfonamide derivatives as potent and orally active ChemR23 inhibitors with a long-acting effect in cynomolgus monkeys. Bioorg Med Chem. 2022 Feb 15;56:116587.

CoACoA of ChemR23-IN-3
Smiles:C(NS(=O)(=O)C1CC1)(=O)C2=C(SC(N([C@H](C)C3=CC=C(C=C3)C4=C(C=CC(C)=C4)C=5NC(=O)ON5)CC6CC6)=N2)C7CC7

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