CFT1946

CFT1946 is an orally active and selective target ligand for BRAF kinase. CFT1946 is a degrader of mutant BRAFV600E, G469A, G466V and p61-BRAFV600E. CFT1946 can be used in tumor research.


Cat. No.: EX-A7771	Purity: >98%

	Chemical structure of CFT1946

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
25mg	833	in_stock
50mg	1464	in_stock
100mg	2410	in_stock
250mg	4191	in_stock

Send PO to E-mail:[email protected]; or Fax:+86 020 81619670

Discount Request


CAS No.	2882165-79-7
Purity	>98%
Formula	C45H49F2N11O9S
Mol Weight	958.001
Color	Off-white to light yellow
State	solid powder
Solubility	DMSO : 100 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Sowa M E, et al. Preclinical evaluation of CFT1946 as a selective degrader of mutant BRAF for the treatment of BRAF driven cancers[J]. Cancer Research, 2022, 82(12_Supplement): 2158-2158.
CoA	CoA of CFT1946

Smiles:	CN1C(C(C(N(CCC2=O)C(N2)=O)=N1)=C3)=CC(N(CC4)CCC4(O)CC(N5CCC6(C[C@@H](N(C=NC7=CC=C8OC(C(F)=CC=C9N[S](N(C)CC)(=O)=O)=C9C#N)C(C7=C8)=O)CO6)CC5)=O)=C3F


		Search