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Product Information:

CDK8-IN-1

CDK8-IN-1 is a potent and selective CDK8 inhibitor with an IC50 of 3 nM.

Cat. No.: EX-A8653    Purity: >98%
Chemical
Chemical structure of CDK8-IN-1


For research only, Do not use for Human!

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CAS No.1629633-48-2
Purity>98%
FormulaC11H8F3N3O
Mol Weight255.1959
ColorWhite to light brown
Statesolid powder
SolubilityDMSO : 100 mg/mL
Shelf Life>3 years if stored properly
StoragePowder   -20°C, 3 years , 4°C, 2 years ; In solvent   -20°C, 1 month
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1].Han X, et al. Discovery of potent and selective CDK8 inhibitors through FBDD approach. Bioorg Med Chem Lett. 2017 Sep 15;27(18):4488-4492.

CoACoA of CDK8-IN-1
Smiles:NC(C1=C(C(F)(F)F)C(C2=CC=NC=C2)=CN1)=O

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