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Product Information:

CDK8/19-IN-2

CDK8/19-IN-2 (compound 12) is an orally active and potent cyclin-dependent kinase 8/19 (CDK8 and CDK19) inhibitor, with IC50 values of 2.08 and 2.49 nM, respectively. CDK8/19-IN-2 can be used for acute myeloid leukemia (AML), breast cancer, and lymphoma research.

Cat. No.: EX-A12197    Purity: >98%
Chemical
Chemical structure of CDK8/19-IN-2


For research only, Do not use for Human!

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CAS No.3024381-54-9
Purity>98%
FormulaC17H20Br2F2N4O
Mol Weight494.172
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Xu J, et al. Discovery of a Novel and Potent Cyclin-Dependent Kinase 8/19 (CDK8/19) Inhibitor for the Treatment of Cancer. J Med Chem. 2024 May 23;67(10):8161-8171.

CoACoA of CDK8/19-IN-2

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