CDK7-IN-30

CDK7-IN-30 (Compound 22) is a CDK7 inhibitor (IC50 = 7.21 nM) that effectively inhibits the phosphorylation of RNA Polymerase II and CDK2. CDK7-IN-30 CDK7-IN-30 can induce cell apoptosis and has anti-cancer activity and can be used in cancer research.


Cat. No.: EX-A10613	Purity: >98%

	Chemical structure of CDK7-IN-30

For research only, Do not use for Human!

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CAS No.	3040999-70-7
Purity	>98%
Formula	C21H28ClN5O3S
Mol Weight	465.997
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Zhang H, et al. Design, Synthesis, and Biological Evaluation of 2, 4-Diaminopyrimidine Derivatives as Potent CDK7 Inhibitors[J]. ACS Medicinal Chemistry Letters, 2024.
CoA	CoA of CDK7-IN-30

Smiles:	N(C1=C(S(C(C)C)(=O)=O)C=CC=C1)C2=NC(N[C@@H]3CC[C@@H](NC(C)=O)CC3)=NC=C2Cl


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