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Product Information:

CDK7-IN-29

CDK7-IN-29 (compound 20) is an inhibitor of CDK7 with an IC50 value of 1.4 nM. CDK7-IN-29 has oral activity and good pharmacokinetic (PK) properties.

Cat. No.: EX-A10614    Purity: >98%
Chemical
Chemical structure of CDK7-IN-29


For research only, Do not use for Human!

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CAS No.3024545-83-0
Purity>98%
FormulaC21H21N5OS
Mol Weight391.489
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Hongjin Zhang, et al. Design, synthesis and evaluation of thieno[3,2-d]pyrimidine derivatives as novel potent CDK7 inhibitors. Bioorg Chem. 2024 Jul:148:107456.

CoACoA of CDK7-IN-29
Smiles:O=C1C2(C=3C(N1)=CC(=CC3)C=4C=5C(SC4)=CN=C(N[C@H]6CCCNC6)N5)CC2

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