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Product Information:

CDK4/6-IN-2

CDK4/6-IN-2 is a potent CDK4 and CDK6 inhibitor extracted from patent US20180000819A1, Compound 1, has IC50s of 2.7 and 16 nM for CDK4 and CDK6, respectively .

Cat. No.: EX-A10504    Purity: >98%
Chemical
Chemical structure of CDK4/6-IN-2


For research only, Do not use for Human!

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CAS No.1800506-48-2
Purity>98%
FormulaC27H32F2N8
Mol Weight506.5934
ColorWhite to off-white
StateSolid
Solubilitysoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder -20℃ 3 years, 4℃ 2 years; In solvent -20℃ 1 year;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Frank Wu, et al. Kinase inhibitor and use thereof. US20180000819A1.

CoACoA of CDK4/6-IN-2
Smiles:CCN1CCN(CC2=CN=C(NC3=NC=C(F)C(C4=CC(N(C(C)C)C(C)=N5)=C5C(F)=C4)=C3)N=C2)CC1

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