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Product Information:

CD532 hydrochloride

CD532 hydrochloride is a potent Aurora A kinase inhibitor with an IC50 of 45 nM. CD532 hydrochloride has the dual effect of blocking Aurora A kinase activity and driving degradation of MYCN. CD532 hydrochloride also can directly interact with AURKA and induces a global conformational shift. CD532 hydrochloride can be used for the research of cancer.

Cat. No.: EX-A8075A    Purity: >98%
Chemical
Chemical structure of CD532 hydrochloride


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
500mg1106In-stock
1g1825In-stock
5gget quoteInquire


CAS No.2926498-81-7
Purity>98%
FormulaC26H26ClF3N8O
Mol Weight558.986
ColorWhite to off-white
Statesolid powder
SolubilityDMSO : 100 mg/mL
Shelf Life>1 years if stored properly
Storage4°C, sealed storage, away from moisture
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Gustafson WC, et, al. Drugging MYCN through an allosteric transition in Aurora kinase A. Cancer Cell. 2014 Sep 8;26(3):414-427.

[2]. Lee JK, et, al. N-Myc Drives Neuroendocrine Prostate Cancer Initiated from Human Prostate Epithelial Cells. Cancer Cell. 2016 Apr 11;29(4):536-547.

CoACoA of CD532 hydrochloride

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