CD38-IN-78c

CD38 inhibitor 1 (compound 78c, CD38-IN-78c, MDK-7553) is a potent inhibitor of CD38 with IC50 of 7.3 nM and 1.9 nM for human CD38 and mouse CD38, respetively.


Cat. No.: EX-A3980	Purity: >98%

	Chemical structure of CD38-IN-78c

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	400	In-stock
250mg	650	In-stock
500mg	950	In-stock
1g	1450	In-stock
2g	2300	In-stock
5g	4350	In-stock

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Synonyms	MDK-7553
Synonyms 2	CD38 inhibitor 1 (compound 78c)
CAS No.	1700637-55-3
Purity	>98%
Formula	C22H27N3O3S
Mol Weight	413.533
State	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Haffner CD, et al. Discovery, Synthesis, and Biological Evaluation of Thiazoloquin(az)olin(on)es as Potent CD38 Inhibitors. J Med Chem. 2015 Apr 23;58(8):3548-71. [2]. Tarragó, Mariana G et al. “A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline.” Cell metabolism vol. 27,5 (2018): 1081-1095.e10.
CoA	CoA of CD38-IN-78c

Smiles:	O=C1N(C)C2=C(C=C(C3=CN=CS3)C=C2)C(N[C@H]4CC[C@H](OCCOC)CC4)=C1


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