CCT365623 hydrochloride

CCT365623 hydrochloride is an orally active lysyl oxidase (LOX) inhibitor, with an IC50 of 0.89 μM. CCT365623 hydrochloride suppresses EGFR (pY1068) and AKT phosphorylation driven by EGF. CCT365623 hydrochloride is extremely well tolerated, and has good pharmacokinetic properties.


Cat. No.: EX-A9452A	Purity: >98%

	Chemical structure of CCT365623 hydrochloride

For research only, Do not use for Human!

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CAS No.	2126136-98-7
Purity	>98%
Formula	C18H18ClNO4S3
Mol Weight	443.988
Color	White to yellow
State	solid
Solubility	DMSO : 250 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder 4°C, sealed storage, away from moisture; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Tang H, et al. Author Correction: Lysyl oxidase drives tumour progression by trapping EGF receptors at the cell surface. Nat Commun. 2019 Jul 18;10(1):3151.
CoA	CoA of CCT365623 hydrochloride

Smiles:	NCC1=CC=C(S(=O)(C2=CC(C3=CC=CC=C3)=CC(S(=O)(C)=O)=C2)=O)S1.Cl


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