CCT018159

CCT018159, a 3,4-diaryl pyrazoleresorcinol, is a ATP-competitive HSP90 ATPase activity inhibitor with IC50s of 3.2 and 6.6 µM for human Hsp90β and yeast Hsp90, respectively. CCT018159 caused cell cytostasis associated with a G1 arrest and induces apoptosis. CCT018159 inhibits key endothelial and tumor cell functions implicated in invasion and angiogenesis .


Cat. No.: EX-A15649	Purity: >98%

	Chemical structure of CCT018159

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	436	in-stock
250mg	652	in-stock
500mg	887	in-stock
1g	1365	in-stock
2g	2342	in-stock
5g	get quote	in-stock

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Synonyms	CCT-018159
Synonyms 2	CCT 018159
CAS No.	171009-07-7
Purity	>98%
Formula	C20H20N2O4
Mol Weight	352.3838
Color	White to off-white
State	Solid
Solubility	soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4℃, sealed storage, protect from light,　2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Swee Y Sharp, et al. In vitro biological characterization of a novel, synthetic diaryl pyrazole resorcinol class of heat shock protein 90 inhibitors. Cancer Res. 2007 Mar 1;67(5):2206-16.
CoA	CoA of CCT018159

Smiles:	CC1=C(C2=CC3=C(OCCO3)C=C2)C(C4=CC(CC)=C(O)C=C4O)=NN1


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