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Product Information:

CC618

CC618 is a potent and selective PPARβ/δ antagonist. CC618 selectively antagonizes agonist-induced PPARβ/δ activity with an IC50 = 10.0 μM.

Cat. No.: EX-A5888    Purity: >98%
Chemical
Chemical structure of CC618


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg985In-stock
100mg1385In-stock
250mg1985In-stock
1gget quoteIn-stock
5gget quoteInquire


SynonymsCC-618
CAS No.1680204-90-3
Purity>98%
FormulaC20H15F6N3O3S2
Mol Weight523.472
ColorWhite to off-white
Statesolid powder
SolubilitySoluble in DMSO ? 25 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Kaupang, Åsmund et al. “Synthesis of 5-trifluoromethyl-2-sulfonylpyridine PPARβ/δ antagonists: Effects on the affinity and selectivity towards PPARβ/δ.” Bioorganic & medicinal chemistry vol. 24,2 (2016): 247-60.

[1]. Kaupang, Åsmund et al. “Synthesis, biological evaluation and molecular modeling studies of the PPARβ/δ antagonist CC618.” European journal of medicinal chemistry vol. 94 (2015): 229-36.

CoACoA of CC618

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