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Product Information:

CC-99282

CC-99282 (Golcadomide) is a potent and orally active cereblon (CRBN) E3 ligase modulator (CELMoD). CC-99282 co-opts CRBN to induce potent and targeted degradation of Ikaros and Aiolos. Golcadomide can be used for researching non-Hodgkin lymphomas.

Cat. No.: EX-A6835    Purity: >98%
Chemical
Chemical structure of CC-99282


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg880In-stock
250mg1480In-stock
500mg2280In-stock
1g4250In-stock
5gget quoteIn-stock


SynonymsGolcadomide
CAS No.2379572-34-4
Purity>98%
FormulaC28H30FN5O5
Mol Weight535.5667
ColorLight yellow to yellow
Statesolid powder
SolubilitySoluble in DMSO 125 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 3 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. J.-M. Michot, et al. A PHASE 1, MULTICENTER, OPEN-LABEL STUDY OF CC-99282 ALONE AND IN COMBINATION WITH RITUXIMAB IN PATIENTS WITH RELAPSED OR REFRACTORY NON-HODGKIN LYMPHOMAS. Hematological Oncology. Volume 39, Issue S2, Jun. 2021.

[2]. Fuchs, Ota. Targeting cereblon in hematologic malignancies. Blood reviews, 100994. 31 Jul. 2022

CoACoA of CC-99282

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