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Product Information:

CC-3240

CC-3240 (compound 13) is a molecular glue degrader of CaMKK2 based on CC-8977, with the IC50 of 9 nM.

Cat. No.: EX-A8394    Purity: >98%
Chemical
Chemical structure of CC-3240


For research only, Do not use for Human!

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CAS No.2922675-91-8
Purity>98%
FormulaC52H64N6O7S
Mol Weight917.166
ColorWhite to off-white
Statesolid powder
SolubilityDMSO : 100 mg/mL
Shelf Life>3 years if stored properly
StoragePowder   -20°C, 3 years , 4°C, 2 years ; In solvent    -20°C, 1 month
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Chen Y, et al. Identification of Small Molecule Inhibitors and Ligand Directed Degraders of Calcium/Calmodulin Dependent Protein Kinase Kinase 1 and 2 (CaMKK1/2). J Med Chem. 2023;66(23):15750-15760.

CoACoA of CC-3240
Smiles:O(CCCCCCCCCC(N[C@H](C(=O)N1[C@H](C(NCC2=CC=C(C=C2)C=3SC=NC3C)=O)C[C@@H](O)C1)[C@](C)(C)C)=O)C4=CC5=C(C(=NC=N5)C6=CC(=C(C(O)=O)C=C6)C7CCCC7)C=C4

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