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Product Information:

CC-223

Onatasertib (CC-223) is a potent, selective, and orally bioavailable inhibitor of mTOR kinase, with an IC50 value for mTOR kinase of 16 nM. Onatasertib inhibits both mTORC1 and mTORC2.

Cat. No.: EX-A8313    Purity: >98%
Chemical
Chemical structure of CC-223


For research only, Do not use for Human!

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SynonymsOnatasertib
Synonyms 2ATG-008
CAS No.1402453-64-8
Purity>98%
FormulaC21H27N5O3
Mol Weight397.4708
ColorLight yellow to yellow
Statesolid powder
SolubilityDMSO : 50 mg/mL
Shelf Life>3 years if stored properly
StoragePowder   -20°C, 3 years ; In solvent    -20°C, 1 year
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1].Mortensen DS, et al. CC-223, a Potent and Selective Inhibitor of mTOR Kinase: In Vitro and In Vivo Characterization. Mol Cancer Ther. 2015 Jun;14(6):1295-305.

CoACoA of CC-223
Smiles:O=C1N(C=2C(NC=C(N2)C=3C=CC(C(C)(C)O)=NC3)=NC1)[C@H]4CC[C@H](OC)CC4

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