CBD3063

CBD3063 is a selective modulator of collapsin response mediator protein 2 (CRMP2). CBD3063 uncouples Cav2.2 from CRMP2. CBD3063 reverses neuropathic and inflammatory pain by reducing membrane expression of CaV2.2 .


Cat. No.: EX-A8428	Purity: >98%

	Chemical structure of CBD3063

For research only, Do not use for Human!

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CAS No.	1281060-70-5
Purity	>98%
Formula	C16H25N5O2
Mol Weight	319.402
Color	White to light brown
State	solid powder
Solubility	H2O : 100 mg/mL DMSO : 4.11 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1].Gomez K, et, al. A peptidomimetic modulator of the CaV2.2 N-type calcium channel for chronic pain. Proc Natl Acad Sci U S A. 2023 Nov 21;120(47):e2305215120. [2].Allen HN, et, al. Uncoupling the CRMP2-CaV2.2 Interaction Reduces Pain-Like Behavior in a Preclinical Joint-Pain Model. J Pain. 2024 Sep 2:104664.
CoA	CoA of CBD3063

Smiles:	O=C(N1CC(NC(C)=O)CCC1)NCCCNC2=NC=CC=C2


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