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Product Information:

CB07-Exatecan

CB07-Exatecan is an ADC drug-Linker conjugate that can be used for the synthesis of ADCs. ADC conjugated with CB07-Exatecan and trastuzumab inhibits the growth of HER2-positive cancer cells.

Cat. No.: EX-A12522    Purity: >98%
Chemical
Chemical structure of CB07-Exatecan


For research only, Do not use for Human!

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CAS No.2879247-31-9
Purity>98%
FormulaC71H94FN11O22
Mol Weight1472.565
ColorLight yellow to yellow
Statesolid
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder 4℃, sealed storage, away from moisture and light, 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Weijia Tang, et al. Method for treating her2-positive solid tumor. Patent WO2023198079A1. /p>

CoACoA of CB07-Exatecan
Smiles:N(C(OCC1=CC=C(NC([C@@H](NC([C@@H](NC([C@@H](NC(CN2C(=O)C=CC2=O)=O)CCNC(CCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)C(C)C)=O)CCCNC(N)=O)=O)C=C1)=O)[C@@H]3C4=C5C(C=6N(C5)C(=O)C7=C(C6)[C@](CC)(O)C(=O)OC7)=NC=8C4=C(CC3)C(C)=C(F)C8

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