CAY10499

CAY10499 (MAGL-IN-5) is a non-selective lipase inhibitor with IC50 values of 144 nM and 14 nM for monoacylglycerol lipase (MAGL) and fatty acid amide hydrolase (FAAH), respectively. Additionally, CAY10499 exhibits anti-inflammatory and antiviral activities.


Cat. No.: EX-A6711	Purity: >98%

	Chemical structure of CAY10499

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
500mg	1462	In-stock
1g	2396	In-stock
5g	get quote	In-stock

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CAS No.	359714-55-9
Purity	>98%
Formula	C18H17N3O5
Mol Weight	355.3447
Color	Off-white to yellow
State	solid powder
Solubility	Soluble in DMSO ? 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder 4°C, protect from light; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Zhuan Q, et al. Cytoplasm lipids can be modulated through hormone-sensitive lipase and are related to mitochondrial function in porcine IVM oocytes. Reprod Fertil Dev. 2020 Apr;32(7):667-675. [2]. Baek YB, et al. Therapeutic strategy targeting host lipolysis limits infection by SARS-CoV-2 and influenza A virus. Signal Transduct Target Ther. 2022 Oct 17;7(1):367. [3]. Muccioli GG, et al. CAY10499, a novel monoglyceride lipase inhibitor evidenced by an expeditious MGL assay. Chembiochem. 2008 Nov 3;9(16):2704-10. [4]. Granchi C, et al. 4-Aryliden-2-methyloxazol-5(4H)-one as a new scaffold for selective reversible MAGL inhibitors. J Enzyme Inhib Med Chem. 2016;31(1):137-46.
CoA	CoA of CAY10499


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