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Product Information:

Cathepsin L Inhibitor I

Cathepsin L Inhibitor I is a potent, cell-permeable, and irreversible inhibitor of cathepsin L.

Cat. No.: EX-A4898    Purity: 98+%
Chemical
Chemical structure of Cathepsin L Inhibitor I


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
10mg585In-stock
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SynonymsZ-FF-FMK
Synonyms 2Z-Phe-Phe-FMK
CAS No.108005-94-3
Purity98+%
FormulaC27H27FN2O4
Mol Weight462.5127
Colorwhite
Statesolid
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Ravanko, K., et al. Cysteine cathepsins are central contributors of invasion by cultured adenosylmethionine decarboxylase-transformed rodent fibroblasts Cancer Res . 2004 Dec 15;64(24):8831-8.

[2]. Esser, R.E., et al. Cysteine proteinase inhibitors decrease articular cartilage and bone destruction in chronic inflammatory arthritis. Arthritis Rheum . 1994 Feb;37(2):236-47.

[3]. Shaw, E., The affinity-labelling of cathepsin S with peptidyl diazomethyl ketones. Comparison with the inhibition of cathepsin L and calpain. FEBS Lett . 1993 Nov 22;334(3):340-2.
CoACoA of Cathepsin L Inhibitor I
Smiles:C1=CC=C(C=C1)CC(C(=O)CF)NC(=O)C(CC2=CC=CC=C2)NC(=O)OCC3=CC=CC=C3

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