Product Information:
| Cat. No.: EX-A4898 | Purity: 98+% |
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| Chemical structure of Cathepsin L Inhibitor I |
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| Synonyms | Z-FF-FMK |
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| Synonyms 2 | Z-Phe-Phe-FMK |
| CAS No. | 108005-94-3 |
| Purity | 98+% |
| Formula | C27H27FN2O4 |
| Mol Weight | 462.5127 |
| Color | white |
| State | solid |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Storage | Powder -20℃ 2 years; In solvent -20℃ 1 month; |
| Shipping | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Reference: | [1]. Ravanko, K., et al. Cysteine cathepsins are central contributors of invasion by cultured adenosylmethionine decarboxylase-transformed rodent fibroblasts Cancer Res . 2004 Dec 15;64(24):8831-8.
[2]. Esser, R.E., et al. Cysteine proteinase inhibitors decrease articular cartilage and bone destruction in chronic inflammatory arthritis. Arthritis Rheum . 1994 Feb;37(2):236-47. [3]. Shaw, E., The affinity-labelling of cathepsin S with peptidyl diazomethyl ketones. Comparison with the inhibition of cathepsin L and calpain. FEBS Lett . 1993 Nov 22;334(3):340-2. |
| CoA | CoA of Cathepsin L Inhibitor I |
| Smiles: | C1=CC=C(C=C1)CC(C(=O)CF)NC(=O)C(CC2=CC=CC=C2)NC(=O)OCC3=CC=CC=C3 |
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