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Product Information:

Caspase-3-IN-1

Caspase-3-IN-1 (compound 11b) is a potent Caspase-3 inhibitor, with an IC50 of 14.5 nM.

Cat. No.: EX-A11172    Purity: >98%
Chemical
Chemical structure of Caspase-3-IN-1


For research only, Do not use for Human!

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CAS No.872254-32-5
Purity>98%
FormulaC26H25N3O6S
Mol Weight507.558
ColorLight yellow to yellow
Statesolid
SolubilityDMSO : 100 mg/mL
Shelf Life>3 years if stored properly
StoragePowder 4°C, protect from light; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Chu W, et al. N-benzylisatin sulfonamide analogues as potent caspase-3 inhibitors: synthesis, in vitro activity, and molecular modeling studies. J Med Chem. 2005 Dec 1;48(24):7637-47.

CoACoA of Caspase-3-IN-1
Smiles:O=S(C1=CC=C(C(C(C2=O)=O)=C1)N2CC3=CC=C(C=C3)OC)(N4[C@@H](CCC4)COC5=CN=CC=C5)=O

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