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Product Information:

CARM1-IN-1

CARM1-IN-1 is a potent and specific CARM1(Coactivator-associated arginine methyltransferase 1) inhibitor with IC50 of 8.6 uM; shows very low activity against PRMT1 and SET7(IC50 > 600 uM).

Cat. No.: EX-A8256    Purity: >98%
Chemical
Chemical structure of CARM1-IN-1


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg461in_stock
250mg747in_stock
500mg1121in_stock
1g1535in_stock


CAS No.1020399-49-8
Purity>98%
FormulaC26H21Br2NO3
Mol Weight555.258
Coloryellow
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder 4℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Cheng D, et al. Novel 3,5-bis(bromohydroxybenzylidene)piperidin-4-ones as coactivator-associated arginine methyltransferase 1 inhibitors: enzyme selectivity and cellular activity. J Med Chem. 2011 Jul 14;54(13):4928-32.

Data SheetData sheet of CARM1-IN-1
CoACoA of CARM1-IN-1
SDSSDS of CARM1-IN-1
Smiles:O=C1/C(CN(C/C1=C\C2=CC=C(C(Br)=C2)O)CC3=CC=CC=C3)=C/C4=CC=C(C(Br)=C4)O

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