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Product Information:

Capravirine

Capravirine, a non-nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.

Cat. No.: EX-A6254    Purity: >98%
Chemical
Chemical structure of Capravirine


For research only, Do not use for Human!

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CAS No.178979-85-6
Purity>98%
FormulaC20H20Cl2N4O2S
Mol Weight451.369
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Li, X et al. “The HIV-1 non-nucleoside reverse transcriptase inhibitors (part V): capravirine and its analogues.” Current medicinal chemistry vol. 19,36 (2012): 6138-49.

[2]. Bu, Hai-Zhi et al. “Evaluation of capravirine as a CYP3A probe substrate: in vitro and in vivo metabolism of capravirine in rats and dogs.” Drug metabolism and disposition: the biological fate of chemicals vol. 35,9 (2007): 1593-602.

[3]. Bu, Hai-Zhi et al. “A unique example of drug metabolism: tetra- and penta-oxygenation reactions of capravirine in rats, dogs and humans.” Drug metabolism letters vol. 1,1 (2007): 61-5.

[4]. Bu, Hai-Zhi et al. “Identification of enzymes responsible for primary and sequential oxygenation reactions of capravirine in human liver microsomes.” Drug metabolism and disposition: the biological fate of chemicals vol. 34,11 (2006): 1798-802.

CoACoA of Capravirine

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