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Cap-dependent endonuclease-IN-3

Suraxavir marboxil (GP681; Cap-dependent endonuclease-IN-3) is a PA subunit cap-dependent endonuclease inhibitor with antiviral activity. Suraxavir marboxil inhibits PA subunit cap-dependent endonuclease activity and inhibits influenza A and/or influenza B viral replication. Suraxavir marboxil can be used alone or in combination with other anti-influenzal agents for the prevention of influenza A and/or influenza B viral infectious diseases. Suraxavir marboxil can be used for the research of influenza A and/or influenza B viral infectious diseases .

Cat. No.: EX-A15629    Purity: >98%
Chemical
Chemical structure of Cap-dependent endonuclease-IN-3


For research only, Do not use for Human!

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SynonymsSuraxavir marboxil
Synonyms 2GP681
CAS No.2364589-86-4
Purity>98%
FormulaC29H25F2N3O7S
Mol Weight597.587
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Li Chen, et al. Pyridone derivative, composition thereof and application thereof as anti-influenza drug. WO2019141179A1. 2020-07-17

CoACoA of Cap-dependent endonuclease-IN-3
Smiles:O=C1N2[C@](N(N3C1=C(OCOC(OC)=O)C(=O)C=C3)[C@H]4C=5C(CSC=6C4=CC=CC6)=C(F)C(F)=CC5)(COC7(C2)CC7)[H]

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