Calpain Inhibitor XII

(Rac)-Calpain Inhibitor XII is a reversible and selective inhibitor of calpain I (μ-calpain, Ki=19 nM). (Rac)-Calpain Inhibitor XII has lower affinities for calpain II (m-calpain, Ki=120 nM) and cathepsin B (Ki=750 nM). (Rac)-Calpain Inhibitor XII has the potential for studying the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling, and cardiac response to injury.


Cat. No.: EX-A6690	Purity: >98%

	Chemical structure of Calpain Inhibitor XII

For research only, Do not use for Human!

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CAS No.	181769-57-3
Purity	>98%
Formula	C26H34N4O5
Mol Weight	482.572
Color	White to yellow
State	solid powder
Solubility	Soluble in DMSO 16 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20°C, stored under nitrogen; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Z Li, et al. Novel peptidyl alpha-keto amide inhibitors of calpains and other cysteine proteases. J Med Chem. 1996 Sep 27;39(20):4089-98.
CoA	CoA of Calpain Inhibitor XII


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