Cabazitaxel

Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity. Cabazitaxel binds to and stabilizes tubulin, resulting in the inhibition of microtubule depolymerization and cell division, cell cycle arrest in the G2/M phase, and the inhibition of tumor cell proliferation. Unlike other taxane compounds, this agent is a poor substrate For the membrane-associated, multidrug resistance (MDR), P-glycoprotein (P-gp) efflux pump and may be useful For treating multidrug-resistant tumors. In addition, cabazitaxel penetrates the blood-brain barrier (BBB).


Cat. No.: EX-A838	Purity: >99%

	Chemical structure of Cabazitaxel

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
5g	785	In-stock
10g	1385	In-stock
25g	2350	In-stock

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CAS No.	183133-96-2
Purity	>99%
Formula	C45H57NO14
Mol Weight	835.9324

CoA	CoA of Cabazitaxel

Smiles:	CO[C@H]1C[C@H]2OC[C@@]2(OC(C)=O)[C@H]2[C@H](OC(=O)C3=CC=CC=C3)[C@]3(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C4=CC=CC=C4)C(C)=C([C@@H](OC)C(=O)[C@]12C)C3(C)C


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