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Product Information:

CAA0225

CAA-0225 is a tissue protease L inhibitor that inhibits rat liver tissue protease L with a IC50 value of 1.9 nM. CAA-0225 can participate in the degradation of autophagosome membrane markers LC3-II and GABARAP , improve cardiac function in mice with reperfusion injury, and kill and eliminate Trypanosoma brucei parasites.

Cat. No.: EX-A14921    Purity: >98%
Chemical
Chemical structure of CAA0225


For research only, Do not use for Human!

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CAS No.244072-26-2
Purity>98%
FormulaC28H29N3O5
Mol Weight487.547
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Characterization of CAA0225, a Novel Inhibitor Specific for Cathepsin L, as a Probe for Autophagic Proteolysis

CoACoA of CAA0225
Smiles:O=C([C@H]1O[C@@H]1C(N[C@@H](CC2=CC=CC=C2)C(NCC3=CC=CC=C3)=O)=O)NCCC4=CC=C(O)C=C4

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