CA/MAO-B-IN-1

CA/MAO-B-IN-1 (Compound 78) is a dual inhibitor for human brain carbonic anhydrases (CA) and Monoamine Oxidase-B (MAO-B), with IC50s of 8.8 and 7.0 nM, respectively. CA/MAO-B-IN-1 reveals a human oral absorption of 71.9% through in silico prediction.


Cat. No.: EX-A12932	Purity: >98%

	Chemical structure of CA/MAO-B-IN-1

For research only, Do not use for Human!

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CAS No.	3038173-64-4
Purity	>98%
Formula	C17H15NO5S
Mol Weight	345.37
Color	White to off-white
State	Solid
Solubility	DMSO : 175 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Giovannuzzi S, et al., Dual Inhibitors of Brain Carbonic Anhydrases and Monoamine Oxidase-B Efficiently Protect against Amyloid-β-Induced Neuronal Toxicity, Oxidative Stress, and Mitochondrial Dysfunction. J Med Chem. 2024 Mar 14;67(5):4170-4193.
CoA	CoA of CA/MAO-B-IN-1

Smiles:	O=C1OC=2C=C(OCC3=CC=C(C=C3)S(=O)(=O)N)C=CC2C=C1C


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