CA-074 methyl ester

CA-074 methyl ester(CA-074Me; CA-074 Me) is a specific inhibitor of Cathepsin B, which has potent bioactivities such as neuroprotective, anti-cancer, and anti-inflamatory effects.


Cat. No.: EX-A1196	Purity: >98%

	Chemical structure of CA-074 methyl ester

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	550	In-stock
250mg	900	In-stock
500mg	1350	In-stock
1g	2150	In-stock
2g	3500	In-stock
3g	4200	In-stock

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Synonyms	CA-074Me
Synonyms 2	CA-074 Me
CAS No.	147859-80-1
Purity	>98%
Formula	C19H31N3O6
Mol Weight	397.4659
State	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Xu Y, et al. Protective mechanisms of CA074-me (other than cathepsin-B inhibition) against programmed necrosis induced by global cerebral ischemia/reperfusion injury in rats. Brain Res Bull. 2016 Jan;120:97-105 [2]. Patel N, et al. CA-074Me compound inhibits osteoclastogenesis via suppression of the NFATc1 and c-FOS signaling pathways. J Orthop Res. 2015 Oct;33(10):1474-86 [3]. Zhang L, et al. Treatment with CA-074Me, a Cathepsin B inhibitor, reduces lung interstitial inflammation and fibrosis in a rat model of polymyositis. Lab Invest. 2015 Jan;95(1):65-77
CoA	CoA of CA-074 methyl ester

Smiles:	CCCNC(=O)[C@H]1O[C@@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1CCC[C@H]1C(=O)OC


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