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Product Information:

BW 245C

BW 245C is a prostanoid DP-receptor (DP1) agonist, used to study stroke.

Cat. No.: EX-A11199    Purity: >98%
Chemical
Chemical structure of BW 245C


For research only, Do not use for Human!

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CAS No.72814-32-5
Purity>98%
FormulaC19H32N2O5
Mol Weight368.4678
Color White to off-white
Statesolid
SolubilityDMSO : 50 mg/mL
Shelf Life>3 years if stored properly
StoragePowder -20℃ 3 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Ahmad AS, et al. PGD2 DP1 receptor stimulation following stroke ameliorates cerebral blood flow and outcomes. Neuroscience. 2014 Oct 24;279:260-8.

[2]. Zhang S, et al. Prostaglandin D2 receptor D-type prostanoid receptor 2 mediates eosinophil trafficking into the esophagus. Dis Esophagus. 2014 Aug;27(6):601-6.

[3]. Ayabe S, et al. Prostaglandin D2 inhibits collagen secretion from lung fibroblasts by activating the DP receptor. J Pharmacol Sci. 2013;121(4):312-7. Epub 2013 Mar 29.

[4]. Kobayashi K, et al. Prostaglandin D2-DP signaling promotes endothelial barrier function via the cAMP/PKA/Tiam1/Rac1 pathway. Arterioscler Thromb Vasc Biol. 2013 Mar;33(3):565-71.

CoACoA of BW 245C
Smiles:O=C(O)CCCCCC[C@@H](C(N1)=O)N(CC[C@H](C2CCCCC2)O)C1=O

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