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Product Information:

Bulevirtide

Bulevirtide is a novel virion entry inhibitor which blocks the virion's hepatocyte pathway of entry, the hepatic sodium/taurocholate cotransporting polypeptide (NTCP) receptor, and is now a promising therapy for both infections.

Cat. No.: EX-A7414    Purity: >98%
Chemical
Chemical structure of Bulevirtide


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
25mg700In-stock
50mg1100In-stock
100mg1700In-stock
250mg2500In-stock
500mg3600In-stock
1g4800In-stock


SynonymsMyrcludex B
CAS No.2012558-47-1
Purity>98%
FormulaC248H355N65O72
Mol Weight5398.8647
ColorWhite to off-white
Statesolid powder
SolubilityH2O : 83.33 mg/mL DMSO : 50 mg/mL
Shelf Life>3 years if stored properly
Storage

Powder -80℃ 3 years;

Powder -20℃ 2 years;

ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Urban, Stephan et al. “Strategies to inhibit entry of HBV and HDV into hepatocytes.” Gastroenterology vol. 147,1 (2014): 48-64. doi:10.1053/j.gastro.2014.04.030

[2]. Donkers, Joanne M et al. “Mechanistic insights into the inhibition of NTCP by myrcludex B.” JHEP reports : innovation in hepatology vol. 1,4 278-285. 1 Aug. 2019, doi:10.1016/j.jhepr.2019.07.006

[3]. Yardeni, D, and C Koh. “Bulevirtide for HBV and HDV infections.” Drugs of today (Barcelona, Spain : 1998) vol. 57,7 (2021): 433-448. doi:10.1358/dot.2021.57.7.3283861

Data SheetData sheet of Bulevirtide
CoACoA of Bulevirtide
SDSSDS of Bulevirtide

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