BTZO-1

BTZO-1 binds to macrophage migration inhibitory factor (MIF) with Kd of 68.6 nM. BTZO-1 activats antioxidant response element (ARE)-mediated gene expression and suppresses oxidative stress-induced cardiomyocyte apoptosis in vitro.


Cat. No.: EX-A4889	Purity: 98+%

	Chemical structure of BTZO-1

For research only, Do not use for Human!

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CAS No.	99420-15-2
Purity	98+%
Formula	C13H8N2OS
Mol Weight	240.28
State	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Haruhide Kimura, et al. BTZO-1, a cardioprotective agent, reveals that macrophage migration inhibitory factor regulates ARE-mediated gene expression. Chem Biol. 2010 Dec 22;17(12):1282-94. PMID: 21168764
CoA	CoA of BTZO-1

Smiles:	C1=CC=C2C(=C1)C(=O)N=C(S2)C3=CC=CC=N3


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