BTK inhibitor 17

BTK inhibitor 17 is a potent and orally active irreversible BTK inhibitor with an IC50 of 2.1 nM. BTK inhibitor 17 can be used for rheumatoid arthritis research.


Cat. No.: EX-A11520	Purity: >98%

	Chemical structure of BTK inhibitor 17

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
250mg	960	In-stock
500mg	1345	In-stock
1g	1885	In-stock

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CAS No.	1858206-76-4
Purity	>98%
Formula	C25H24N6O3
Mol Weight	456.4965
Color	White to off-white
State	Solid
Solubility	DMSO : 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20℃ 3 years; 4℃, 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Xuejun Zhang, et al. Discovery and Evaluation of Pyrazolo[3,4- d]pyridazinone as a Potent and Orally Active Irreversible BTK Inhibitor. ACS Med Chem Lett. 2019 Dec 11;11(10):1863-1868.
CoA	CoA of BTK inhibitor 17

Smiles:	O=C1C=2N(N=C(C2C(N)=NN1)C3=CC=C(OC4=CC=CC=C4)C=C3)[C@H]5CN(C(C=C)=O)CCC5


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