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Product Information:

BTK-IN-48

BTK-IN-48 is a BTK inhibitor with an IC50 of 1.14 μM. BTK-IN-48 inhibits recombinant BTK and c-Src, and exerts moderate inhibitory effects on LCK, BMX/ETK, FLT3 and PIM1. BTK-IN-48 can be used in the research of B-cell malignancies and autoimmune diseases .

Cat. No.: EX-A17395    Purity: >98%
Chemical
Chemical structure of BTK-IN-48


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
5mg585Inquire
10mg685Inquire
25mg985Inquire


CAS No.3114078-55-3
Purity>98%
FormulaC19H15N3O3
Mol Weight333.3407
 
 
Reference:  

[1].Kim Y, et al. Discovery of novel imidazo[4,5-b]pyridine derivatives as noncovalent reversible Bruton's tyrosine kinase inhibitors. Bioorg Med Chem Lett. 2026 Mar;132:130497.

CoACoA of BTK-IN-48
Smiles:COC(C=C1)=CC=C1N(C(C2=CC=C(O)C=C2O)=N3)C4=C3C=CC=N4

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