BRD0705

BRD0705 is a potent, paralog selective and orally active inhibitor of GSK3α with IC50 of 66 nM and Kd of 4.8 μM. BRD0705 can be used for acute myeloid leukemia (AML).


Cat. No.: EX-A4670	Purity: >98%

	Chemical structure of BRD0705

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	975	In-stock
100mg	1550	In-stock
250mg	2550	In-stock
1g	get quote	In-stock
5g	23500	In-stock

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CAS No.	2056261-41-5
Purity	>98%
Formula	C20H23N3O
Mol Weight	321.4161
State	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. FF Wagner et al. Exploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia. Sci Transl Med. 2018 Mar 7;10(431).
CoA	CoA of BRD0705


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