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Product Information:

BRD 4354 ditrifluoroacetate

BRD 4354 (ditrifluoroacetate) is a moderately potent inhibitor of HDAC5 and HDAC9, with IC50s of 0.85 and 1.88 μM, respectively.

Cat. No.: EX-A9808A    Purity: >98%
Chemical
Chemical structure of BRD 4354 ditrifluoroacetate


For research only, Do not use for Human!

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CAS No.2444837-63-0
Purity>98%
FormulaC25H25ClF6N4O5
Mol Weight610.933
Colorlight yellow to yellow
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder 4℃, sealed storage, away from moisture, 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Boskovic ZV, ET AL. Inhibition of Zinc-Dependent Histone Deacetylases with a Chemically Triggered Electrophile. ACS Chem Biol. 2016 Jul 15;11(7):1844-51.

CoACoA of BRD 4354 ditrifluoroacetate
Smiles:OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CCN1CCN(CC1)C(C1=CN=CC=C1)C1=CC(Cl)=C2C=CC=NC2=C1O

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