BPKDi

BPKDi is an inhibitor of PKD. BPKDi inhibits three members of the PKD family, PKD1, PKD2, and PKD3, with IC50 values of 1 nM, 9 nM, and 1 nM, respectively. BPKDi blocks signal-dependent phosphorylation and nuclear export of class IIa HDACs in cardiomyocytes and concomitantly suppresses hypertrophy of these cells.


Cat. No.: EX-A11075	Purity: >98%

	Chemical structure of BPKDi

For research only, Do not use for Human!

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CAS No.	1201673-28-0
Purity	>98%
Formula	C21H28N6O
Mol Weight	380.4866
Color	Off-white to light yellow
State	Solid
Solubility	DMSO : 50 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder 4℃, sealed storage, away from moisture and light; In solvent -20℃ 1 month;

Reference:	[1]. Lauren Monovich, et al. A novel kinase inhibitor establishes a predominant role for protein kinase D as a cardiac class IIa histone deacetylase kinase. FEBS Lett. 2010 Feb 5;584(3):631-7.
CoA	CoA of BPKDi

Smiles:	O=C(N)C1=CC(C2=CC(NC3CCCCC3)=NC=C2)=NC(N4CCNCC4)=C1


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