BPK-25

BPK-25, an active acrylamide, promotes degradation of nucleosome remodeling and deacetylation (NuRD) complex proteins by a post-translational mechanism involving covalent protein engagement. BPK-25 inhibits TMEM173 activation by the cyclic dinucleotide ligand cGAMP .


Cat. No.: EX-A8396	Purity: >98%

	Chemical structure of BPK-25

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
25mg	650	Inquire
50mg	950	Inquire
100mg	1350	Inquire
1g	get quote	Inquire
5g	get quote	bulk discount

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CAS No.	2305052-86-0
Purity	>98%
Formula	C21H17ClN4O2
Mol Weight	392.838
Color	Off-white to light yellow
State	solid powder
Solubility	DMSO : 150 mg/mL
Shelf Life	>1 years if stored properly
Storage	4°C, sealed storage, away from moisture
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1].Ekaterina V Vinogradova, et al. An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells. Cell. 2020 Aug 20;182(4):1009-1026.e29.
CoA	CoA of BPK-25

Smiles:	O=C(C=C)N(C1=CN=C(C=C1)C(=O)NC=2C=CC=CC2)CC3=NC(Cl)=CC=C3


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