BPHA

BPHA is a potent and orally active MMP-2, MMP-9 and MMP-14 inhibitor with IC50s of 12 nM, 16 nM and 17 nM, respectively. BPHA does not inhibit MMP-1, -3, and -7 (the IC50s are 974, >1000, and 795 nM, respectively). BPHA has antiangiogenic and antitumor effects.


Cat. No.: EX-A11044	Purity: >98%

	Chemical structure of BPHA

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
250mg	750	In-stock
500mg	1200	Inquire
1g	1920	Inquire

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Synonyms	MMP-9 Inhibitor II
Synonyms 2	MMP-2
CAS No.	193807-60-2
Purity	>98%
Formula	C21H20N2O4S
Mol Weight	396.459
Color	White to off-white
State	Solid
Solubility	DMSO : 350 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20℃ 3 years; 4℃, 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. R Maekawa, et al. Correlation of antiangiogenic and antitumor efficacy of N-biphenyl sulfonyl-phenylalanine hydroxiamic acid (BPHA), an orally-active, selective matrix metalloproteinase inhibitor. Cancer Res. 1999 Mar 15;59(6):1231-5.
CoA	CoA of BPHA

Smiles:	O=S(C1=CC=C(C2=CC=CC=C2)C=C1)(N[C@H](CC3=CC=CC=C3)C(NO)=O)=O


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