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BODIPY FL thalidomide

BODIPY FL thalidomide is a high-affinity and selective human cereblon (CRBN)-targeting fluorescent probe with a Kd of 3.6 nM. BODIPY FL thalidomide enables use as a probe in time-resolved fluorescence resonance energy transfer (TR-FRET) binding assays for cereblon ligands. BODIPY FL thalidomide supports development of highly sensitive, selective, stable cereblon TR-FRET binding assays (Ex/Em = 502/510 nm) .

Cat. No.: EX-A8827    Purity: >98%
Chemical
Chemical structure of BODIPY FL thalidomide


For research only, Do not use for Human!

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CAS No.2740620-18-0
Purity>98%
FormulaC37H43BF2N6O7
Mol Weight732.581
ColorOrange to red
StateSolid
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder -20°C 3 years, 4°C 2 years; In solvent -20°C 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Lin W, et al. Development of BODIPY FL Thalidomide As a High-Affinity Fluorescent Probe for Cereblon in a Time-Resolved Fluorescence Resonance Energy Transfer Assay. Bioconjug Chem. 2020;31(11):2564-2575.

CoACoA of BODIPY FL thalidomide

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