BMY7378

BMY 7378 is a selective antagonist of α1D-adrenoceptor (α1D-AR). BMY 7378 binds to membranes expressing the cloned rat α1D-AR with a >100-fold higher affinity (Ki=2 nM) than binding to either the cloned rat α1A-AR (Ki=800 nM) or the hamster α1B-AR (Ki=600 nM). BMY 7378 is a 5-HT1A receptor partial agonist .


Cat. No.: EX-A2035	Purity: >98%

	Chemical structure of BMY7378

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
500mg	650	In-stock
1g	850	In-stock
5g	2550	In-stock
10g	3980	In-stock

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Synonyms	BMY 7378
CAS No.	21102-95-4
Purity	>98%
Formula	C22H33Cl2N3O3
Mol Weight	458.422
Color	white to off-white
State	powder
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4℃,4℃, sealed storage, away from moisture and light , 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Piascik MT, et al. The specific contribution of the novel alpha-1D adrenoceptor to the contraction of vascular smooth muscle. J Pharmacol Exp Ther. 1995;275(3):1583-1589. [2]. Goetz AS, et al. BMY 7378 is a selective antagonist of the D subtype of alpha 1-adrenoceptors. Eur J Pharmacol. 1995;272(2-3):R5-R6.
CoA	CoA of BMY7378

Smiles:	Cl.Cl.COC1=CC=CC=C1N1CCN(CCN2C(=O)CC3(CCCC3)CC2=O)CC1


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